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Med-books.by - Библиотека медицинской литературы

Medical Genetics at a Glance - Pritchard Dorian, Korf Bruce R. - 2003 год



Medical Genetics at a Glance - Pritchard Dorian, Korf Bruce R. - 2003 год

This book is written primarily for medical students seeking a summary of genetics and its medical applications, but it should be of value also to
advanced students in the biosciences, paramedical scientists, established medical doctors and health professionals who need to extend or
update their knowledge. It should be of especial value to those preparing for examinations.

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Medical Genetics. Its Application to Speech, Hearing and Craniofacial Disorders - Robin Nathaniel H. - 2008 год



Medical Genetics. Its Application to Speech, Hearing and Craniofacial Disorders - Robin Nathaniel H. - 2008 год

Nowhere in the literature is there a book that reviews the rapidly developing field medical genetics from theories to its implications for clinical practice. Nathaniel Robin's book fills that void. His new book covers the whole field of medical genetics from a general overview of the profession to details of effective treatment of patients with common and esoteric genetic disorders including birth defects, hearing loss, oro-facial clefting, craiosynostosis, and much more. Crucially, as issues surrounding breakthroughs in understanding and development of new technologies in genetics have risen to the fore of the cultural consciousness, he gives coverage to the many ethical questions raised.

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Molecular Basis for Mitochondrial Signaling - Rostovtseva T.K. - 2017 год



Molecular Basis for Mitochondrial Signaling - Rostovtseva T.K. - 2017 год

This book covers recent advances in the study of structure, function, and regulation of metabolite, protein and ion translocating channels, and transporters in mitochondria. A wide array of cuttingedge methods are covered, ranging from electrophysiology and cell biology to bioinformatics, as well as structural, systems, and computational biology. At last, the molecular identity of two important channels in the mitochondrial inner membrane, the mitochondrial calcium uniporter and the mitochondrial permeability transition pore have been established. After years of work on the physiology and structure of VDAC channels in the mitochondrial outer membrane, there have been multiple discoveries on VDAC permeation and regulation by cytosolic proteins. Recent breakthroughs in structural studies of the mitochondrial cholesterol translocator reveal a set of novel unexpected features and provide essential clues for defining therapeutic strategies. Molecular Basis for Mitochondrial Signaling covers these and many more recent studies of mitochondria function, their communication with other organelles, and their critical roles in development, aging, and in a plethora of stressful or degenerative events. Authored by leading researchers in the field, this volume will be an indispensable reference resource for graduate students and academics working in related areas of biophysics and cell biology as well as for professionals within industry.

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Ion Channel Diseases - Rouleau G., Gaspar C. - 2008 год



Ion Channel Diseases - Rouleau G., Gaspar C. - 2008 год

Ion channel dysfunction in humans leads to impairment of the excitable processes necessary for the normal function of several tissues, such as muscle and brain. It follows that an increasing number of human diseases have been associated with malfunctioning ion channels, many of which have a genetic component.
This volume of Advances in Genetics presents a broad and comprehensive overview of the inherited channelopathies in humans, including clinical, genetic and molecular aspects of these conditions. Keeping true to the scope of the serial, novel genomic and modeling research approaches and a review of potential therapeutic approaches for each of these conditions are also incorporated.

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Movement Disorder Genetics - Schneider S.A., Tomás Brás J.M. - 2015 год



Movement Disorder Genetics - Schneider S.A., Tomás Brás J.M. - 2015 год

This book covers recent developments and possible pitfalls in the diagnosis of genetic movement disorders and related conditions. It is divided into three sections: technical and scientific aspects; clinical aspects with guidance towards work-up; and ethical and legal aspects of genetic testing in a clinical and research setting.
The first section includes chapters on genetic analysis and counselling with critical discussion of potential problems when interpreting the results. Clinical chapters summarize genetic forms of movement disorders including parkinsonism, tics and dystonia with algorithms for hands-on daily practice. Related conditions such as RLS, ataxias and dementias are also covered. Finally, chapters on ethical and legal aspects of genetic testing are included.
Movement Disorder Genetics is aimed at clinicians and scientists working in the field of movement disorders and related conditions.

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Textbook of Human Reproductive Genetics - Sermon K., Viville S. - 2014 год



Textbook of Human Reproductive Genetics - Sermon K., Viville S. - 2014 год

What happens with our genome and epigenome in the first fundamental days of our development? How can this be analysed? What do we need to know when faced with patients' questions about their own infertility, or how to prevent the birth of affected children? For the first time, this book brings together both scientists' and clinicians' viewpoints on human reproductive genetics, making for a more comprehensive discussion of interest to ART professionals and developmental biologists. With worldwide leaders in this burgeoning field guiding the reader through from the basics to the most exciting recent discoveries, this book presents the wider picture of how reproductive medicine and biology links with genetics. The editors also address the new challenges raised in how to treat and counsel patients at fertility and genetic clinics, as well as eliciting vivid bioethical debates. This book brings together genetics, reproductive biology and medicine for practitioners and geneticists.

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Biochemical Basis and Therapeutic Implications of Angiogenesis - Mehta J., Mathur P., Dhalla N.S. - 2017 год



Biochemical Basis and Therapeutic Implications of Angiogenesis - Mehta J., Mathur P., Dhalla N.S. - 2017 год

This book covers the latest developments in the therapeutic implications of angiogenesis, ranging from angiogenesis in the brain, angiogenesis in cancer, angiogenesis' role in atherosclerosis and heart disease as well as metabolic disorders and peripheral vascular disease.
The book is comprehensive in its coverage of angiogenesis in a diverse set of diseases and examines the role of cellular and subcellular structures during the development of angiogenesis. Well-organized and thorough, this is an ideal book for researchers and biomedical engineers working in the field of therapeutic implications of angiogenesis.

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Informed Consent in Predictive Genetic Testing: A Revised Model - Minor J. - 2015 год



Informed Consent in Predictive Genetic Testing: A Revised Model - Minor J. - 2015 год

This important book proposes revising the current informed consent protocol for predictive genetic testing to reflect the trend toward patient-centered medicine. Emphasizing the predictive aspect of testing, the author analyzes the state of informed consent procedure in terms of three components: comprehension of risk assessment, disclosure to select appropriate treatment, and voluntariness. The book's revised model revisits these cornerstones, restructuring the consent process to allow for expanded comprehension time, enhanced patient safety, greater patient involvement and autonomy, and reduced chance of coercion by family or others. A comparison of the current and revised versions and case studies showing the new model in real-world applications add extra usefulness to this resource.

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Apoptotic and Non-apoptotic Cell Death - Nagata S., Nakano H. - 2017 год



Apoptotic and Non-apoptotic Cell Death - Nagata S., Nakano H. - 2017 год

This volume focuses on apoptotic and non-apoptotic programmed cell death, including necroptosis, pyroptosis, and ferroptosis, and presents recent findings in the field. It discusses the crucial role that apoptotic and non-apoptotic cell death play in various pathological conditions, such as skin diseases, inflammatory bowel diseases, and virus infections. Further, it highlights the mechanisms underlying the recognition and clearance of dead cells, and the subsequent biological responses triggered by phagocytosed macrophages and factors released from dying cells. Offering insights into cell death, it is a valuable resource for researchers and clinicians developing novel strategies to treat various diseases that are closely associated with cell death.

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